Miconazole in Systemic Mycosis

Neonatal systemic candidiasis treated with miconazole.

Systemic mycosis caused by a new Cladophialophora species.

A 22-year-old woman suffered from haemoptyses of unknown aetiology. A tumour in the lingula was diagnosed histologically to be a granulomatosis, most likely a sarcoidosis. Two years later, the patient returned with dyspnoea caused by a granulomatous tumour in the trachea, histologically similar to that seen earlier. After bronchoscopic laser resection, cortisone therapy was applied but without ...

Neonatal systemic candidiasis: a failure to respond to intravenous miconazole in two neonates.

a superimposed nutritional deficiency which further impairs their resistance, especially to diarrhoeal disease. This suggests that one important cause of postneonatal mortality in Latin America is low birthweight, possibly as a result of poor maternal health and nutritional status. In other parts of the world-for example in Africa and the Indian subcontinent-the prevalence of low birthweight is...

Neonatal systemic candidiasis : a failure to respond to intravenous miconazole in two neonates

myocardial lesions.7 No nodules in the central nervous system have been described. Cases without visceral nodules (the multiple group) demonstrate a wide range of involvement from single bony or subcutaneous nodules to widespread involvement of skin, subcutaneous tissue, muscle, and bone. As ultimate regression is the rule survival is assured. The difficulty in making a pathological diagnosis l...

Bioassay for miconazole.

A radial diffusion bioassay for miconazole, which employs Candida stellatoidea as the indicator organism, is described. Results from three patients treated with the drug are presented.